Search results for "Outdoor activity"

showing 3 items of 3 documents

Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error

2016

Myopia is the most common human eye disorder and it results from complex genetic and environmental causes. The rapidly increasing prevalence of myopia poses a major public health challenge. Here, the CREAM consortium performs a joint meta-analysis to test single-nucleotide polymorphism (SNP) main effects and SNP × education interaction effects on refractive error in 40,036 adults from 25 studies of European ancestry and 10,315 adults from 9 studies of Asian ancestry. In European ancestry individuals, we identify six novel loci (FAM150B-ACP1, LINC00340, FBN1, DIS3L-MAP2K1, ARID2-SNAT1 and SLC14A2) associated with refractive error. In Asian populations, three genome-wide significant loci AREG…

0301 basic medicineRefractive errorgenetic structuresGeneral Physics and AstronomyGenome-wide association studyVARIANTSrefractive error ; geneEYEBioinformaticsINCIDENT MYOPIAGenome-wide association studiesSensory disorders Donders Center for Medical Neuroscience [Radboudumc 12]0302 clinical medicinePolymorphism (computer science)10. No inequalityPOPULATIONeducation.field_of_studyMultidisciplinaryQACTIVATED PROTEIN-KINASEta3142single-nucleotide polymorphismRETINAL-PIGMENT EPITHELIUMOUTDOOR ACTIVITY3142 Public health care science environmental and occupational health3. Good healthRefractive errorsMeta-analysislociEducational StatusSciencePopulation610 Medicine & healthEnvironmentBiologyta3111Polymorphism Single NucleotideArticleWhite PeopleGeneral Biochemistry Genetics and Molecular BiologyEducation03 medical and health sciencesAsian PeopleSDG 3 - Good Health and Well-beingGenetic variationmedicineHumansSNPGenetic Predisposition to Diseasemyopia3125 Otorhinolaryngology ophthalmologyGenetic variationeducationRECEPTORGene Expression Profilingta1184General ChemistryHeritabilitymedicine.diseaseeye diseasesta3125TIME OUTDOORS030104 developmental biologyGenetic LociEvolutionary biologyRISK-FACTORS030221 ophthalmology & optometryREsense organs3111 BiomedicineGenome-Wide Association StudyNature Communications
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The effect of out-of-home activity intervention delivered by volunteers on depressive symptoms among older people with severe mobility limitations: a…

2015

Objectives: To examine the effects of an individualized outdoor activity intervention carried out by volunteers on depressive symptoms among community-living older people with severe mobility limitations who have difficulties accessing the outdoors independently. Methods: Secondary analyses of the “Volunteering, Access to Outdoor Activities and Wellbeing in Older People” (VOW) data (ISRCTN56847832). VOW was a randomized single blinded two-arm controlled trial conducted in Jyväskylä, Finland, in 2009-2011. At baseline, 121 people aged 67-92 years with severe mobility limitations were interviewed at home and randomized into either an intervention or waiting list control group. Volunteers (n=4…

GerontologyMaleVolunteersmedicine.medical_specialtyMotor Activitylaw.inventionolder peopleRandomized controlled trialRecreation TherapylawIntervention (counseling)EpidemiologyActivities of Daily LivingMedicineout-of-home activityHumansOutdoor activityMobility LimitationVolunteerDepression (differential diagnoses)AgedAged 80 and overbusiness.industryDepressioninterestsinterests.interestta3142Middle AgedPsychiatry and Mental healthvolunteeringTreatment OutcomeMobility LimitationdepressionPhysical therapyRecreationFemaleGeriatrics and GerontologyPshychiatric Mental HealthbusinessOlder peopleGerontologyAgingmental health
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Changes in life-space mobility and quality of life among community-dwelling older people: a 2-year follow-up study

2016

Purpose Life-space mobility refers to the spatial area in which a person moves in daily life, taking into account distance, frequency and assistance needed. The aim was to examine how changes in life-space mobility are associated with changes in quality of life (QOL) over a 2-year period. Methods Community-dwelling people aged 75–90 years (n = 848) were interviewed face-to-face in their homes and followed up annually for 2 years. QOL was assessed with the short version of the World Health Organization QOL assessment (range 0–130, higher scores indicate better QOL). Life-space mobility was assessed with the Life-Space Assessment (range 0–120, higher scores indicate better life-space mobility…

MaleGerontologyAgingmedicine.medical_specialtyhyvinvointiNeuropsychological Testscomputer.software_genreWorld health03 medical and health sciences0302 clinical medicineQuality of lifelife-spacemedicineHumansCognitive Dysfunction030212 general & internal medicineMobility Limitationskin and connective tissue diseasesAgedosallistuminenAged 80 and overGeriatricsbusiness.industryData CollectionPublic healthagingPublic Health Environmental and Occupational HealthFollow up studies3. Good healthGeriatricsLife spaceoutdoor activityWell-beingQuality of LifeRegression AnalysisFemalesense organsSelf ReportData miningbusinessOlder peoplecomputer030217 neurology & neurosurgeryFollow-Up StudiesQuality of Life Research
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